Derivado cinamoílico com atividade no reparo de DNA e outras substâncias de Cinnamomum australe (Lauraceae)


Autoria(s): Carbonezi,Carlos Alberto; Lopes,Márcia Nasser; Silva,Dulce Helena Siqueira; Araújo,Ângela Regina; Bolzani,Vanderlan da Silva; Young,Maria Claudia Marx; Silva,Marcelo Rogério da
Data(s)

01/04/2004

Resumo

The bioactive compound trans-3'-methylsulphonylallyl trans-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-delta8'-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the leaves of Cinnamomum australe. The structures of these compounds were assigned by analysis of 1D and 2D NMR data and comparison with data registered in the literature for these compounds. The DNA-damaging activity of 1 is being described for the first time.

Formato

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Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000200005

Idioma(s)

pt

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.27 n.2 2004

Palavras-Chave #Cinnamomum australe #Lauraceae #DNA-damaging activity
Tipo

journal article