New antagonist agents of neuropeptide y receptors


Autoria(s): Aldana,Ignacio; Rivero,Isabel; Rivero,Argimiro; Huenchuñir,Patricio; Frigola,Carmen; Alonso,Maria Luisa; Monge,Antonio; Caignard,D. H.; Renard,P.
Data(s)

01/12/2000

Resumo

In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists will be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422000000600005

Idioma(s)

en

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.23 n.6 2000

Palavras-Chave #obesity #energy metabolism #weight reduction #neuropeptide Y
Tipo

journal article