Síntese de β-cetoésteres cíclicos: novo procedimento para ciclizações de Dieckmann empregando ALCL3 e trietilamina


Autoria(s): Peçanha,Emerson P.; Barreiro,Eliezer J.; Fraga,Carlos A. M.
Data(s)

01/08/1997

Resumo

In this communication we describe a new methodology to Dieckmann cyclization of diethyl adipate (1) and diethyl pimelate (3) applying "push-pull" strategy using anhydrous aluminium trichloride and triethylamine in dichloromethane at room temperature. This method is very efficient, simple, safe and reproducible, giving the corresponding cyclic β-keto ester derivatives in 84% and 71% yield, respectively.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421997000400016

Idioma(s)

pt

Publicador

Sociedade Brasileira de Química

Fonte

Química Nova v.20 n.4 1997

Palavras-Chave #Dieckmann cyclization #cyclopentanone derivatives #cyclohexanone derivatives
Tipo

journal article