Reuse of information for selection of methods and operating conditions for drying of pharmaceutical materials


Autoria(s): Chekuri, Rahul
Data(s)

09/06/2008

09/06/2008

2007

Resumo

Drying is a major step in the manufacturing process in pharmaceutical industries, and the selection of dryer and operating conditions are sometimes a bottleneck. In spite of difficulties, the bottlenecks are taken care of with utmost care due to good manufacturing practices (GMP) and industries' image in the global market. The purpose of this work is to research the use of existing knowledge for the selection of dryer and its operating conditions for drying of pharmaceutical materials with the help of methods like case-based reasoning and decision trees to reduce time and expenditure for research. The work consisted of two major parts as follows: Literature survey on the theories of spray dying, case-based reasoning and decision trees; working part includes data acquisition and testing of the models based on existing and upgraded data. Testing resulted in a combination of two models, case-based reasoning and decision trees, leading to more specific results when compared to conventional methods.

Identificador

http://www.doria.fi/handle/10024/38705

Idioma(s)

en

Palavras-Chave #Case-based reasoning #decision trees and spray drying technology
Tipo

Diplomityö

Master's thesis