Pyroptosis: Caspase-11 Unlocks the Gates of Death.
| Data(s) |
2015
|
|---|---|
| Resumo |
How inflammatory caspases trigger pyroptotic cell death is mostly unexplained. In this issue of Immunity, Núñez and colleagues report that caspase-11 cleaves the transmembrane channel pannexin-1, causing an efflux of cellular ATP that promotes a P2X7 receptor-dependent pyroptosis. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_6E958EED3865 isbn:1097-4180 (Electronic) pmid:26588774 doi:10.1016/j.immuni.2015.10.024 isiid:000366846000003 |
| Idioma(s) |
en |
| Fonte |
Immunity, vol. 43, no. 5, pp. 835-837 |
| Tipo |
info:eu-repo/semantics/article article |
