Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections.
| Data(s) |
2015
|
|---|---|
| Resumo |
We described for the first time the amino acid substitutions conferring rifampicin resistance in eight Propionibacterium acnes strains isolated from patients with biofilm or device-related infections. We identified different mutations in cluster I and one mutation, never reported, in cluster II of the rpoB gene (I480V) associated with the most frequent one in cluster I (S442L). Half of the patients previously received treatment with rifampicin. |
| Identificador |
https://serval.unil.ch/?id=serval:BIB_2F40B4E02F57 isbn:1095-8274 (Electronic) pmid:25999299 doi:10.1016/j.anaerobe.2015.05.003 isiid:000358098600017 |
| Idioma(s) |
en |
| Fonte |
Anaerobe, vol. 34, pp. 116-119 |
| Palavras-Chave | #Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Bacterial Agents/pharmacology; Biofilms; Catheter-Related Infections/microbiology; DNA-Directed RNA Polymerases/genetics; Drug Resistance, Bacterial; Female; Gram-Positive Bacterial Infections/microbiology; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Propionibacterium acnes/drug effects; Propionibacterium acnes/isolation & purification; Rifampin/pharmacology; Sequence Analysis, DNA |
| Tipo |
info:eu-repo/semantics/article article |
