Preparation of benzolactams by Pd(II)-catalyzed carbonylation of N-unprotected arylethylamines
| Contribuinte(s) |
Universitat de Barcelona |
|---|---|
| Resumo |
An unprecedented NH2-directed Pd(II)-catalytic carbonylation of quaternary aromatic α -amino esters to yield 6-membered 10 benzolactams has been developed. The reaction shows a strong bias to 6-membered lactams over 5-membered ones. The steric hindrance around the amino group seems to be pivotal for the success of the process. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Royal Society of Chemistry |
| Direitos |
(c) López, Blanca et al., 2011 info:eu-repo/semantics/openAccess |
| Palavras-Chave | #Pal·ladi (Element químic) #Química organometàl·lica #Reaccions químiques #Lactames #Imines #Palladium #Organometallic chemistry #Chemical reactions #Lactams #Imines |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion |
