An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines


Autoria(s): Amat Tusón, Mercedes; Pérez Bosch, Maria; Minaglia, Annamaria T.; Bosch Cartes, Joan
Contribuinte(s)

Universitat de Barcelona

Resumo

A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.

Identificador

http://hdl.handle.net/2445/36346

Idioma(s)

eng

Publicador

American Chemical Society

Direitos

(c) American Chemical Society , 2008

info:eu-repo/semantics/openAccess

Palavras-Chave #Compostos organometàl·lics #Coure #Síntesi orgànica #Lactames #Organometallic compounds #Copper #Synthetic organic chemistry #Lactams
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/acceptedVersion