Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

Autoria(s): van der Linden J.W.; Arendrup M.C.; Warris A.; Lagrou K.; Pelloux H.; Hauser P.M.; Chryssanthou E.; Mellado E.; Kidd S.E.; Tortorano A.M.; Dannaoui E.; Gaustad P.; Baddley J.W.; Uekötter A.; Lass-Flörl C.; Klimko N.; Moore C.B.; Denning D.W.; Pasqualotto A.C.; Kibbler C.; Arikan-Akdagli S.; Andes D.; Meletiadis J.; Naumiuk L.; Nucci M.; Melchers W.J.; Verweij P.E.
Data(s)

2015
Resumo

To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromising clinical use of azoles.
Identificador

http://serval.unil.ch/?id=serval:BIB_3A0070929AE7

isbn:1080-6059 (Electronic)

pmid:25988348

doi:10.3201/eid2106.140717

isiid:000355386900018
Idioma(s)

en
Fonte

Emerging Infectious Diseases, vol. 21, no. 6, pp. 1041-1044
Tipo

info:eu-repo/semantics/article

article
Acesso ao item digital