Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions
| Contribuinte(s) |
Universitat de Barcelona |
|---|---|
| Data(s) |
20/12/2013
|
| Resumo |
A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
John Wiley & Sons |
| Direitos |
(c) John Wiley & Sons, 2010 info:eu-repo/semantics/embargoedAccess |
| Palavras-Chave | #Trastorns del metabolisme dels lípids #Bioquímica #Aldehids #Disseny de medicaments #Medicina nuclear #Lipid metabolism disorders #Biochemistry #Aldehydes #Drug design #Nuclear medicine |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/submittedVersion |
