A molecular profile of T-cell exhaustion in cancer.
| Data(s) |
2012
|
|---|---|
| Resumo |
The first gene profiling study of cancer-specific CD8+ T-cells demonstrates that lymphocyte dysfunction in cancer tissue is due to multiple molecular alterations,(1) similar as in "exhausted" T-cells in chronic infection.(2) The data suggest novel drug targets, and show that T-cell exhaustion is reversible and limited to anatomical sites of disease. |
| Identificador |
https://serval.unil.ch/?id=serval:BIB_FEDF76FCECC4 isbn:2162-4011 (Print) pmid:22737618 doi:10.4161/onci.18342 http://my.unil.ch/serval/document/BIB_FEDF76FCECC4.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FEDF76FCECC43 |
| Idioma(s) |
en |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Oncoimmunology, vol. 1, no. 3, pp. 369-371 |
| Tipo |
info:eu-repo/semantics/article article |
