Complementary DNA cloning of complement C8 beta and its sequence homology to C9.
| Data(s) |
01/06/1987
|
|---|---|
| Resumo |
The complete amino acid sequence of mature C8 beta has been derived from the DNA sequence of a cDNA clone identified by expression screening of a human liver cDNA library. Comparison with the amino acid sequence of C9 shows an overall homology with few deletions and insertions. In particular, the cysteine-rich domains and membrane-inserting regions of C9 are well conserved. These findings are discussed in relation to a possible mechanism of membrane attack complex formation. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_FBB52AEAFE2C isbn:0006-2960 (Print) pmid:3651397 doi:10.1021/bi00386a045 isiid:A1987H856800045 |
| Idioma(s) |
en |
| Fonte |
Biochemistry, vol. 26, no. 12, pp. 3551-3556 |
| Palavras-Chave | #Amino Acid Sequence; Base Sequence; Cloning, Molecular; Complement C8/genetics; Complement C9/genetics; DNA/analysis; Humans; Liver/metabolism; Macromolecular Substances; Sequence Homology, Nucleic Acid |
| Tipo |
info:eu-repo/semantics/article article |
