Phosphorylation of CARMA1: the link(er) to NF-kappaB activation.
| Data(s) |
2005
|
|---|---|
| Resumo |
Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-kappaB. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_EE535738DC3E isbn:1074-7613[print], 1074-7613[linking] pmid:16356853 doi:10.1016/j.immuni.2005.11.007 isiid:000234316900001 |
| Idioma(s) |
en |
| Fonte |
Immunity, vol. 23, no. 6, pp. 551-553 |
| Palavras-Chave | #Animals; Apoptosis Regulatory Proteins/metabolism; CARD Signaling Adaptor Proteins; Guanylate Kinase/metabolism; Immunity, Cellular/physiology; NF-kappa B/metabolism; Phosphorylation; Protein Kinase C/metabolism; Receptors, Antigen/metabolism; Signal Transduction/immunology; Transcriptional Activation/immunology |
| Tipo |
info:eu-repo/semantics/article article |
