Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.

Autoria(s): Rajesh M.; Mukhopadhyay P.; Haskó G.; Liaudet L.; Mackie K.; Pacher P.
Data(s)

2010
Identificador

http://serval.unil.ch/?id=serval:BIB_EBEA7C0C4FC4

isbn:1476-5381[electronic], 0007-1188[linking]

pmid:20590572

doi:10.1111/j.1476-5381.2010.00712.x

isiid:000277914700024
Idioma(s)

en
Fonte

British Journal of Pharmacology, vol. 160, no. 3, pp. 688-700
Palavras-Chave #Acetylcysteine/pharmacology; Arachidonic Acids/antagonists & inhibitors; Arachidonic Acids/pharmacology; Cell Death/drug effects; Cell Death/physiology; Cell Line; Coronary Vessels/drug effects; Coronary Vessels/metabolism; Dose-Response Relationship, Drug; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Humans; Mitogen-Activated Protein Kinases/metabolism; Morpholines/pharmacology; Piperidines/pharmacology; Polyunsaturated Alkamides/antagonists & inhibitors; Polyunsaturated Alkamides/pharmacology; Pyrazoles/pharmacology; Reactive Oxygen Species/metabolism; Receptor, Cannabinoid, CB1/agonists; Signal Transduction/drug effects; Signal Transduction/physiology; Tetrahydrocannabinol/analogs & derivatives; Tetrahydrocannabinol/pharmacology
Tipo

info:eu-repo/semantics/article

article
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