Chronic obstructive pulmonary disease in never-smoking animal farmers working inside confinement buildings


Autoria(s): Monso Eduard; Riu Elena; Radon Katja; Magarolas Ramon; Danuser Brigitta; Iversen Martin; Morera Josep; Nowak Dennis
Data(s)

2004

Resumo

BACKGROUND: In animal farming, respiratory disease has been associated with indoor air contaminants and an excess in FEV1 decline. Our aim was to determine the characteristics and risk factors for chronic obstructive pulmonary disease (COPD) in never-smoking European farmers working inside animal confinement buildings. METHODS: A sample of participants in the European Farmers' Study was selected for a cross-sectional study assessing lung function and air contaminants. Dose-response relationships were assessed using logistic regression models. RESULTS: COPD was found in 18 of 105 farmers (45.1 SD 11.7 years) (17.1%); 8 cases (7.6%) with moderate and 3 cases (2.9%) with severe disease. Dust and endotoxin showed a dose-response relationship with COPD, with the highest prevalence of COPD in subjects with high dust (low=7.9%/high=31.6%) and endotoxin exposure (low=10.5%/high=20.0%). This association was statistically significant for dust in the multivariate analysis (OR 6.60, 95% CI 1.10-39.54). CONCLUSION: COPD in never-smoking animal farmers working inside confinement buildings is related to indoor dust exposure and may become severe. [Authors]

Identificador

http://serval.unil.ch/?id=serval:BIB_E58A2AA279A6

isbn:0271-3586

doi:10.1002/ajim.20077

pmid:15376214

isiid:000224405300007

Idioma(s)

en

Fonte

American Journal of Industrial Medicine, vol. 46, no. 4, pp. 357-362

Tipo

info:eu-repo/semantics/article

article