CD4+CD25+Foxp3+ regulatory T cells: from basic research to potential therapeutic use.
| Data(s) |
2007
|
|---|---|
| Resumo |
Regulatory T cells control immune responses to self- and foreign-antigens and play a major role in maintaining the balance between immunity and tolerance. This article reviews recent key developments in the field of CD4+CD25+Foxp3+ regulatory T (TREG) cells. It presents their characteristics and describes their range of activity and mechanisms of action. Some models of diseases triggered by the imbalance between TREG cells and effector pathogenic T cells are described and their potential therapeutic applications in humans are outlined. |
| Identificador |
https://serval.unil.ch/notice/serval:BIB_DA36BD2D338E info:pmid:18027108 https://serval.unil.ch/resource/serval:BIB_DA36BD2D338E.P001/REF http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DA36BD2D338E7 urn:nbn:ch:serval-BIB_DA36BD2D338E7 |
| Idioma(s) |
eng |
| Fonte |
Swiss medical weekly13745-46625-634 |
| Palavras-Chave | #Animals; Antigens, CD; Antigens, Differentiation; Forkhead Transcription Factors; Humans; Immune Tolerance; Interleukin-10; Interleukin-2; Receptors, Interleukin-2; T-Lymphocytes, Regulatory; Transforming Growth Factor beta; Transplantation Immunology |
| Tipo |
info:eu-repo/semantics/review article |
| Formato |
application/pdf |
| Direitos |
info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer |
