Lambert-Eaton myasthenic syndrome revealing an abdominal neuroblastoma.


Autoria(s): de Buys Roessingh A.S.; Loriot M.H.; Wiesenauer C.; Lallier M.
Data(s)

2009

Resumo

Lambert-Eaton myasthenic syndrome is a paraneoplastic syndrome that may reveal a primitive tumor. Neuroblastoma in children and small cell lung carcinoma in adults are the leading tumors revealed or expressed by paraneoplastic phenomena. The clinical neurologic manifestations of Lambert-Eaton myasthenic syndrome are muscular weakness, sleepiness, absence of reflexes, and dysautonomia. Neurologic manifestations are explained by the induction of an autoimmune response because of the presence of antigens that are expressed by the tumor. Neurologic paraneoplastic disorders may also be the result of toxicity of drugs, coagulopathy, infection, or metabolic diseases. We describe the case of a 13-month-old child with unusual neurologic symptoms because of the presence of an abdominal neuroblastoma.

Identificador

http://serval.unil.ch/?id=serval:BIB_D969703A93BA

isbn:1531-5037[electronic]

pmid:19635290

doi:10.1016/j.jpedsurg.2009.04.023

Idioma(s)

en

Fonte

Journal of Pediatric Surgery, vol. 44, no. 8, pp. E5-7

Palavras-Chave #Abdominal Neoplasms/diagnosis; Abdominal Neoplasms/surgery; Diagnosis, Differential; Diagnostic Imaging; Female; Humans; Infant; Lambert-Eaton Myasthenic Syndrome/diagnosis; Lambert-Eaton Myasthenic Syndrome/surgery; Neuroblastoma/diagnosis; Neuroblastoma/surgery
Tipo

info:eu-repo/semantics/article

article