Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists.

Autoria(s): Chowers Y.; Sturm A.; Sans M.; Papadakis K.; Gazouli M.; Harbord M.; Jahnel J.; Mantzaris G.J.; Meier J.; Mottet C.; Peyrin-Biroulet L.; Allez M.
Data(s)

2010
Resumo

This second section of the first ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases addresses the biological roles of TNFα and the effects and mechanisms of action of TNFα antagonists. Mechanisms underlying their failure, including induction of TNF-independent inflammatory pathways and phenomena of paradoxical inflammation are discussed.
Identificador

https://serval.unil.ch/?id=serval:BIB_D2408C003E03

isbn:1876-4479[electronic], 1873-9946[linking]

doi:10.1016/j.crohns.2010.05.011

pmid:21122531

isiid:000284137700002
Idioma(s)

en
Fonte

Journal of Crohn's and Colitis, vol. 4, no. 4, pp. 367-376
Tipo

info:eu-repo/semantics/review

article
Acesso ao item digital