In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.


Autoria(s): Henry P.G.; Adriany G.; Deelchand D.; Gruetter R.; Marjanska M.; Oz G.; Seaquist E.R.; Shestov A.; Uğurbil K.
Data(s)

2006

Resumo

In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients necessary for a dynamic metabolic modeling study, with particular emphasis on practical issues.

Identificador

https://serval.unil.ch/?id=serval:BIB_D04D3CFB5137

isbn:0730-725X[print], 0730-725X[linking]

pmid:16677959

doi:10.1016/j.mri.2006.01.003

isiid:000237711000023

Idioma(s)

en

Fonte

Magnetic Resonance Imaging, vol. 24, no. 4, pp. 527-539

Palavras-Chave #Animals; Brain/metabolism; Carbon Radioisotopes; Magnetic Resonance Spectroscopy; Models, Biological; Rats
Tipo

info:eu-repo/semantics/review

article