Molecular Mechanisms of Acute Brain Injury and Ensuing Neurodegeneration


Autoria(s): Ortega González, Fco. Javier; Vidal Taboada, José Manuel; Mahy Gehenne, Josette Nicole; Rodríguez Allué, Manuel José
Contribuinte(s)

Universitat de Barcelona

Data(s)

18/03/2013

Resumo

Injury to the central nervous system (CNS), including stroke, traumatic brain injury andspinal cord injury, cause devastating and irreversible damage and loss of function. Forexample, stroke affects very large patient populations, results in major suffering for the patients and their relatives, and involves a significant cost to society. CNS damage implies disruption of the intricate internal circuits involved in cognition, the sensory-motor functions, and other important functions. There are currently no treatments available to properly restore such lost functions. New therapeutic proposals will emerge from an understanding of the interdependence of molecular and cellular responses to CNS injury, in particular the inhibitory mechanisms that block regeneration and those that enhanceneuronal plasticity...

Identificador

http://hdl.handle.net/2445/34287

Idioma(s)

eng

Publicador

InTech

Direitos

cc-by (c) Ortega González et al., 2012

info:eu-repo/semantics/openAccess

<a href="http://creativecommons.org/licenses/by/3.0/">http://creativecommons.org/licenses/by/3.0/</a>

Palavras-Chave #Lesions cerebrals #Malalties neurodegeneratives #Brain damage #Neurodegenerative Diseases
Tipo

info:eu-repo/semantics/bookPart