Serial brain (18)FDG-PET in anti-AMPA receptor limbic encephalitis.
| Data(s) |
2014
|
|---|---|
| Resumo |
Immunotherapy-responsive autoimmune CNS syndromes linked to antibodies targeting surface neuronal antigens lack reliable biomarkers of disease activity. We report serial cerebral (18)FDG PET studies in a woman with AMPA receptor (AMPA-R) autoimmune limbic encephalitis. During her follow-up, despite an aggressive immunotherapy, she displayed a persistent, predominantly left hippocampal FDG hypermetabolism, in the absence of CNS inflammatory signs. Brain metabolism abnormalities regressed after increasing antiepileptic treatment, correlating with a moderate clinical improvement. Brain (18)F-FDG PET could thus represent a useful complementary tool to orient the clinical follow-up. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_BCB068E97D53 isbn:1872-8421 (Electronic) pmid:24793897 doi:10.1016/j.jneuroim.2014.04.002 isiid:000337207700008 |
| Idioma(s) |
en |
| Fonte |
Journal of Neuroimmunology, vol. 271, no. 1-2, pp. 53-55 |
| Tipo |
info:eu-repo/semantics/article article |
