Regions of mouse mammary tumor virus superantigen involved in interaction with the major histocompatibility complex class II I-A molecule.
| Data(s) |
2002
|
|---|---|
| Resumo |
To study the major histocompatibility complex class II I-E dependence of mouse mammary tumor virus (MMTV) superantigens, we constructed hybrids between the I-E-dependent MMTV(GR) and the I-E-independent mtv-7 superantigens and tested them in vivo. Our results suggest that, although the C-terminal third mediates I-A interaction, additional binding sites are located elsewhere in the superantigen. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_B68628BAB6DD isbn:0022-538X (Print) pmid:12368363 doi:10.1128/JVI.76.21.11172-11175.2002 isiid:000178512300064 |
| Idioma(s) |
en |
| Fonte |
Journal of Virology, vol. 76, no. 21, pp. 11172-11175 |
| Palavras-Chave | #Amino Acid Sequence; Animals; Antigens, Viral/genetics; Antigens, Viral/immunology; CD4-Positive T-Lymphocytes/immunology; Cell Line; Epitopes, T-Lymphocyte/genetics; Epitopes, T-Lymphocyte/immunology; Histocompatibility Antigens Class II/genetics; Histocompatibility Antigens Class II/immunology; Mammary Tumor Virus, Mouse/genetics; Mammary Tumor Virus, Mouse/immunology; Membrane Glycoproteins/genetics; Membrane Glycoproteins/immunology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Receptors, Antigen, T-Cell, alpha-beta/immunology; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/immunology; Superantigens/genetics; Superantigens/immunology |
| Tipo |
info:eu-repo/semantics/article article |
