Biblioteca Digital

**Autoria(s):** Richards, J.B.; Yuan, X.; Geller, F.; Waterworth, D.; Bataille, V.; Glass, D.; Song, K.; Waeber, G.; Vollenweider, P.; Aben, K.K.; Kiemeney, L.A.; Walters, B.; Soranzo, N.; Thorsteinsdottir, U.; Kong, A.; Rafnar, T.; Deloukas, P.; Sulem, P.; Stefansson, H.; Stefansson, K.; Spector, T.D.; Mooser, V.
Data(s)	2008
Resumo	We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).
Identificador	https://serval.unil.ch/notice/serval:BIB_AFB4769B6AAE info:pmid:18849991 https://serval.unil.ch/resource/serval:BIB_AFB4769B6AAE.P001/REF http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_AFB4769B6AAE2 urn:nbn:ch:serval-BIB_AFB4769B6AAE2
Idioma(s)	eng
Fonte	Nature Genetics40111282-1284
Palavras-Chave	#Alopecia; Chromosomes, Human, Pair 20; Female; Genetic Predisposition to Disease; Genome, Human; Humans; Male; Polymorphism, Single Nucleotide
Tipo	info:eu-repo/semantics/article article
Formato	application/pdf
Direitos	info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer

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