Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes.


Autoria(s): Harraghy N.; Homerova D.; Herrmann M.; Kormanec J.
Data(s)

2008

Resumo

Mapping the transcription start points of the eap, emp, and vwb promoters revealed a conserved octanucleotide sequence (COS). Deleting this sequence abolished the expression of eap, emp, and vwb. However, electrophoretic mobility shift assays gave no evidence that this sequence was a binding site for SarA or SaeR, known regulators of eap and emp.

Identificador

https://serval.unil.ch/?id=serval:BIB_AD9B717B855D

isbn:1098-5530[electronic], 0021-9193[linking]

pmid:17965149

doi:10.1128/JB.01174-07

isiid:000252080400044

Idioma(s)

en

Fonte

Journal of Bacteriology, vol. 190, no. 1, pp. 447-451

Palavras-Chave #Bacterial Proteins/chemistry; Bacterial Proteins/metabolism; Base Sequence; Binding Sites; Conserved Sequence; Extracellular Matrix Proteins/chemistry; Extracellular Matrix Proteins/metabolism; Gene Expression Regulation, Bacterial; Oligodeoxyribonucleotides/chemistry; Promoter Regions, Genetic; Staphylococcus aureus/genetics; Trans-Activators/chemistry; Trans-Activators/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism; Transcription, Genetic
Tipo

info:eu-repo/semantics/article

article