Prospective determination of imipenem concentration of the plasma of critically-ill children
| Contribuinte(s) |
Moreillon P. |
|---|---|
| Data(s) |
2006
|
| Resumo |
ABSTRACT Imipenem plasma-concentrations were measured in 19 critically-ill children (median 0.8 year, range 0.02-12.9 years). Wide inter-individual variations (2-4x at peak and >10x at through concentrations) resulted in unpredictable plasma-levels in several children. To avoid subtherapeutic drug levels we recommend at least 100 mg/kg/day of imipenem-cilastatin in critically-ill children requiring such therapy. |
| Formato |
21 |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_A9F833DEAECB http://my.unil.ch/serval/document/BIB_A9F833DEAECB.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A9F833DEAECB4 |
| Idioma(s) |
en |
| Publicador |
Lausanne: Université de Lausanne, Faculté de biologie et médecine |
| Direitos |
info:eu-repo/semantics/openAccess |
| Palavras-Chave | #Monitoring; Pharmacokinetics; plasma concentration; imipenem-cilastatin; intensive care unit; children |
| Tipo |
info:eu-repo/semantics/doctoralThesis phdthesis |
