DNA topology: feeling the pulse of a topoisomerase.


Autoria(s): Stasiak A.
Data(s)

01/07/2000

Resumo

The action of individual type II DNA topoisomerases has been followed in real time by observing the elastic response of single DNA molecules to sequential strand passage events. Micromanipulation methods provide a complementary approach to biochemical studies for investigating the mechanism of DNA topoisomerases.

Identificador

http://serval.unil.ch/?id=serval:BIB_A2E67BFDAF75

isbn:0960-9822[print], 0960-9822[linking]

pmid:10898993

doi:10.1016/S0960-9822(00)00585-6

isiid:000088979200010

Idioma(s)

en

Fonte

Current Biology, vol. 10, no. 14, pp. R526-R528

Palavras-Chave #Adenosine Triphosphate/metabolism; Animals; DNA Topoisomerases, Type II/metabolism; DNA, Superhelical/chemistry; DNA, Superhelical/metabolism; Models, Biological; Nucleic Acid Conformation
Tipo

info:eu-repo/semantics/review

article