Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death.


Autoria(s): Nazarov A.A.; Gardini D.; Baquié M.; Juillerat-Jeanneret L.; Serkova T.P.; Shevtsova E.P.; Scopelliti R.; Dyson P.J.
Data(s)

2013

Resumo

Two hybrid compounds comprising an antimetastatic ruthenium-arene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed.

Identificador

https://serval.unil.ch/?id=serval:BIB_93112AE121F2

isbn:1477-9234 (Electronic)

pmid:23223548

doi:10.1039/c2dt31936e

isiid:000313804200002

Idioma(s)

en

Fonte

Dalton Transactions (cambridge, England : 2003), vol. 42, no. 7, pp. 2347-2350

Tipo

info:eu-repo/semantics/article

article