Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
| Contribuinte(s) |
Universitat de Barcelona |
|---|---|
| Data(s) |
07/05/2013
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| Resumo |
Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a critical role during the first steps of HIV infection, we investigated the possible impact of α-defensins1-3 production by DC on disease progression. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Public Library of Science (PLoS) |
| Direitos |
cc-by (c) Rodríguez García, M. et al., 2010 info:eu-repo/semantics/openAccess <a href="http://creativecommons.org/licenses/by/3.0/es">http://creativecommons.org/licenses/by/3.0/es</a> |
| Palavras-Chave | #VIH (Virus) #Immunologia #HIV (Viruses) #Immunology |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
