Clonal analysis of the BALB/c T cell proliferative response to apo beef cytochrome c.


Autoria(s): Corradin G.; Zubler R.H.; Engers H.D.
Data(s)

1981

Resumo

Murine T cell clones that proliferated specifically in response to the protein antigen apo cytochrome c were derived and maintained in continuous culture. Two distinct clonotypes were observed with respect to the proliferative responses observed when a variety of peptides prepared from several species of cytochrome c were tested. These 2 clonotypes appeared to recognize 2 different regions in the cytochrome c molecule. Only 1 of the 2 clonotypes tested demonstrated helper cell activity for antibody formation in vitro.

Identificador

http://serval.unil.ch/?id=serval:BIB_91C725E54215

isbn:0022-1767 (Print)

pmid:6271872

isiid:A1981MS29500049

Idioma(s)

en

Fonte

Journal of Immunology, vol. 127, no. 6, pp. 2442-2446

Palavras-Chave #Animals; Antibody Formation; Antibody-Producing Cells/immunology; Apoproteins/immunology; Cattle; Clone Cells/immunology; Cytochrome c Group/pharmacology; Hemolytic Plaque Technique; Horses; Lymph Nodes/immunology; Lymphocyte Activation; Mice; Mice, Inbred BALB C; T-Lymphocytes/immunology; Trinitrobenzenes/immunology
Tipo

info:eu-repo/semantics/article

article