PPAR gamma: ally and foe in bone metabolism.
| Data(s) |
2008
|
|---|---|
| Resumo |
Bone homeostasis is a well-balanced process that is largely dependent on the contribution of both bone-forming osteoblasts and bone-resorbing osteoclasts. A new study (Wan et al., 2007) suggests a previously unsuspected role for the transcription factor PPARgamma in promoting bone progenitors to the osteoclastic lineage. |
| Identificador |
https://serval.unil.ch/?id=serval:BIB_8FFE2B0EC4D7 isbn:1550-4131[print] doi:10.1016/j.cmet.2008.02.005 pmid:18316021 isiid:000253727300002 |
| Idioma(s) |
en |
| Fonte |
Cell Metabolism, vol. 7, no. 3, pp. 188-190 |
| Palavras-Chave | #Animals; Bone Remodeling/drug effects; Bone Resorption/metabolism; Cell Differentiation; Cell Lineage; Hematopoietic Stem Cells/metabolism; Humans; Mice; Mice, Knockout; NF-kappa B/metabolism; Osteoblasts/drug effects; Osteoblasts/metabolism; Osteoclasts/drug effects; Osteoclasts/metabolism; Osteopetrosis/metabolism; PPAR gamma/agonists; PPAR gamma/genetics; Proto-Oncogene Proteins c-fos/metabolism; Signal Transduction/drug effects; Thiazolidinediones/pharmacology |
| Tipo |
info:eu-repo/semantics/article article |
