Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model.

Autoria(s): Yang X.; Mertens B.; Lehtonen E.; Vercammen L.; Bockstael O.; Chtarto A.; Levivier M.; Brotchi J.; Michotte Y.; Baekelandt V.; Sarre S.; Tenenbaum L.
Data(s)

2009
Identificador

http://serval.unil.ch/?id=serval:BIB_8F63F8819274

isbn:1521-2254[electronic], 1099-498X[linking]

pmid:19639608

doi:10.1002/jgm.1377
Idioma(s)

en
Fonte

Journal of Gene Medicine, vol. 11, no. 10, pp. 899-912
Palavras-Chave #Adrenergic Agents/administration & dosage; Adrenergic Agents/adverse effects; Animals; Dependovirus/genetics; Dopamine/analysis; Dopamine/biosynthesis; Doxycycline/administration & dosage; Female; Gene Expression/drug effects; Gene Transfer Techniques; Genetic Vectors/administration & dosage; Genetic Vectors/genetics; Glial Cell Line-Derived Neurotrophic Factor/administration & dosage; Glial Cell Line-Derived Neurotrophic Factor/biosynthesis; Humans; Motor Activity/drug effects; Oxidopamine/administration & dosage; Oxidopamine/adverse effects; Parkinson Disease, Secondary/chemically induced; Parkinson Disease, Secondary/metabolism; Rats; Time Factors; Tyrosine 3-Monooxygenase/analysis; Tyrosine 3-Monooxygenase/biosynthesis
Tipo

info:eu-repo/semantics/article

article
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