T cell homeostasis
| Data(s) |
2008
|
|---|---|
| Resumo |
The pool of mature T cells comprises a heterogeneous mixture of naive and memory CD4(+) and CD8(+) cells. These cells are long lived at a population level but differ markedly in their relative rates of turnover and survival. Here, we review how contact with exogenous stimuli, notably self MHC ligands and various gamma(c) cytokines, plays a decisive role in controlling normal T cell homeostasis. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_868B1BFF4696 isbn:0818-9641 isiid:000255755300007 doi:10.1038/icb.2008.12 pmid:18362947 |
| Idioma(s) |
en |
| Fonte |
Immunology and Cell Biology, vol. 86, no. 4, pp. 312-319 |
| Palavras-Chave | #T cells; cytokines; MHC ligands; thymus; Major histocompatibility complex; chronic viral-infection; phenotype cd8(+) cells; receptor-alpha-chain; in-vivo; autoimmune-disease; cutting edge; selective stimulation; immune-responses ; lymphopenia-induced proliferation; |
| Tipo |
info:eu-repo/semantics/article article |
