Calcifications vasculaires et déficit en vitamine K: un facteur de risque modifiable dans l'insuffisance rénale chronique [Vascular calcifications and vitamin K deficiency: a modifiable risk factor in chronic kidney disease].
| Data(s) |
2013
|
|---|---|
| Resumo |
The mechanisms of vascular calcifications in chronic renal failure are complex. Apart for clotting factors, vitamin K-dependent proteins include matrix Gla protein. Glutamic acid residues in matrix Gla protein are carboxylated by vitamin K-dependent gamma-carboxylase, which enables it to inhibit calcification. The purpose of this review is to discuss available evidence implicating vitamin K as a modifiable risk factor in the pathogenesis of vascular calcification in renal diseases. |
| Identificador |
https://serval.unil.ch/?id=serval:BIB_7C0C1CCD579B isbn:1660-9379 (Print) pmid:23539811 |
| Idioma(s) |
fr |
| Fonte |
Revue Médicale Suisse, vol. 9, no. 375, pp. 451-455 |
| Palavras-Chave | #Effect Modifier, Epidemiologic; Humans; Models, Biological; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic/complications; Renal Insufficiency, Chronic/epidemiology; Risk Factors; Vascular Calcification/epidemiology; Vascular Calcification/etiology; Vitamin K/physiology; Vitamin K Deficiency/complications; Vitamin K Deficiency/epidemiology |
| Tipo |
info:eu-repo/semantics/review article |
