Peroxisome-proliferator-activated receptors and cancers: complex stories.
| Data(s) |
2004
|
|---|---|
| Resumo |
Peroxisome-proliferator-activated receptors (PPARs) are nuclear hormone receptors that mediate the effects of fatty acids and their derivatives at the transcriptional level. Through these pathways, PPARs can regulate cell proliferation, differentiation and survival, so controlling carcinogenesis in various tissues. But what are the links between each PPAR isotype and carcinogenesis and what is the relevance of these findings to human pathology and therapy? |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_76D9CE5EF974 isbn:1474-175X[print], 1474-175X[linking] pmid:14708026 doi:10.1038/nrc1254 isiid:000187742800015 |
| Idioma(s) |
en |
| Fonte |
Nature Reviews. Cancer, vol. 4, no. 1, pp. 61-70 |
| Palavras-Chave | #Humans; Neoplasms/etiology; Neoplasms/physiopathology; Receptors, Cytoplasmic and Nuclear/physiology; Transcription Factors/physiology |
| Tipo |
info:eu-repo/semantics/review article |
