Scientific production on the applicability of phenytoin in wound healing


Autoria(s): Firmino,Flávia; Almeida,Alessandra Maria Pereira de; Silva,Rita de Jesus Grijó e; Alves,Graziela da Silva; Grandeiro,Daniel da Silva; Penna,Lúcia Helena Garcia
Data(s)

01/02/2014

Resumo

Phenytoin is an anticonvulsant that has been used in wound healing. The objectives of this study were to describe how the scientific production presents the use ofphenytoinas a healing agent and to discuss its applicability in wounds. A literature review and hierarchy analysis of evidence-based practices was performed. Eighteen articles were analyzed that tested the intervention in wounds such as leprosy ulcers, leg ulcers, diabetic foot ulcers, pressure ulcers, trophic ulcers, war wounds, burns, preparation of recipient graft area, radiodermatitis and post-extraction of melanocytic nevi. Systemic use ofphenytoinin the treatment of fistulas and the hypothesis of topical use in the treatment of vitiligo were found. In conclusion, topical use ofphenytoinis scientifically evidenced. However robust research is needed that supports a protocol for the use ofphenytoinas another option of a healing agent in clinical practice.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342014000100162

Idioma(s)

en

Publicador

Universidade de São Paulo, Escola de Enfermagem

Fonte

Revista da Escola de Enfermagem da USP v.48 n.1 2014

Palavras-Chave #Phenytoin #Wound healing #Evidence-based nursing #Review
Tipo

journal article