Evaluation of adding a second marker to overcome Staphylococcus aureus spa typing homoplasies.
| Data(s) |
2012
|
|---|---|
| Resumo |
The utility of sequencing a second highly variable locus in addition to the spa gene (e.g., double-locus sequence typing [DLST]) was investigated to overcome limitations of a Staphylococcus aureus single-locus typing method. Although adding a second locus seemed to increase discriminatory power, it was not sufficient to definitively infer evolutionary relationships within a single multilocus sequence type (ST-5). |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_645B864AB800 isbn:1098-660X (Electronic) pmid:22259202 doi:10.1128/JCM.00664-11 isiid:000302148700063 |
| Idioma(s) |
en |
| Fonte |
Journal of Clinical Microbiology, vol. 50, no. 4, pp. 1475-1477 |
| Palavras-Chave | #Adhesins, Bacterial/genetics; Antigens, Bacterial/genetics; Bayes Theorem; Evolution, Molecular; Genetic Markers; Haplotypes; Markov Chains; Models, Genetic; Monte Carlo Method; Multilocus Sequence Typing; Phylogeny; Polymorphism, Single Nucleotide; Staphylococcus aureus/classification; Staphylococcus aureus/genetics |
| Tipo |
info:eu-repo/semantics/article article |
