False-negative PCR result due to gene polymorphism: the example of Neisseria meningitidis.


Autoria(s): Jaton Katia; Ninet Beatrice; Bille Jacques; Greub Gilbert
Data(s)

2010

Resumo

Early treatment of meningococcal meningitis is mandatory but may negate the cerebrospinal fluid culture. Etiological diagnosis then mainly relies on PCR. Here, we report a case of false-negative results for real-time PCR for a Neisseria meningitidis serogroup B isolate with a polymorphism in the ctrA gene.

Identificador

http://serval.unil.ch/?id=serval:BIB_6161402352BF

isbn:1098-660X[electronic], 0095-1137[linking]

pmid:20962143

doi:10.1128/JCM.01766-10

isiid:000284693400039

Idioma(s)

en

Fonte

Journal of Clinical Microbiology, vol. 48, no. 12, pp. 4590-4591

Palavras-Chave #Real-Time PCR; Acid Amplification Tests; Streptococcus-Pneumoniae; Haemophilus-Influenzae; Diagnosis; Identification; Mitis
Tipo

info:eu-repo/semantics/article

article