Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.


Autoria(s): Santuari L.; Pradervand S.; Amiguet-Vercher A.M.; Thomas J.; Dorcey E.; Harshman K.; Xenarios I.; Juenger T.E.; Hardtke C.S.
Data(s)

2010

Resumo

ABSTRACT: Identification of small polymorphisms from next generation sequencing short read data is relatively easy, but detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization signal reliably flags deletions. Interestingly, individual deletions were frequently observed in two or more of the accessions examined, suggesting that variation in gene content partly reflects a common history of deletion events.

Identificador

https://serval.unil.ch/?id=serval:BIB_5A02614F7662

isbn:1465-6914[electronic], 1465-6906[linking]

pmid:20067627

doi:10.1186/gb-2010-11-1-r4

isiid:000276433600012

http://my.unil.ch/serval/document/BIB_5A02614F7662.pdf

http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_5A02614F76620

Idioma(s)

en

Direitos

info:eu-repo/semantics/openAccess

Fonte

Genome Biology, vol. 11, no. 1, pp. R4

Tipo

info:eu-repo/semantics/article

article