Biblioteca Digital

**Autoria(s):** Bello C.; Dal Bello G.; Cea M.; Nahimana A.; Aubry D.; Garuti A.; Motta G.; Moran E.; Fruscione F.; Pronzato P.; Grossi F.; Patrone F.; Ballestrero A.; Dupuis M.; Sordat B.; Zimmermann K.; Loretan J.; Wartmann M.; Duchosal M.A.; Nencioni A.; Vogel P.
Data(s)	2011
Resumo	New derivatives of 1,4-dideoxy-1,4-imino-D-ribitol have been prepared and evaluated for their cytotoxicity on solid and haematological malignancies. 1,4-Dideoxy-5-O-[(9Z)-octadec-9-en-1-yl]-1,4-imino-D-ribitol (13, IC(50) ∼2 μM) and its C(18)-analogues (IC(50) <10 μM) are cytotoxic toward SKBR3 (breast cancer) cells. 13 also inhibits (IC(50) ∼8 μM) growth of JURKAT cells.
Identificador	https://serval.unil.ch/?id=serval:BIB_516406B5E329 isbn:1464-3391 (Electronic) pmid:22079865 doi:10.1016/j.bmc.2011.07.053 isiid:000297860100044
Idioma(s)	en
Fonte	Bioorganic and Medicinal Chemistry, vol. 19, no. 24, pp. 7720-7727
Tipo	info:eu-repo/semantics/article article

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