Use of the comet test to assess DNA damage in children with ataxia-telangiectasia and their relatives.


Autoria(s): Moreno Galarraga, L; Santos Pérez, J L; Ramirez-Tortosa, M C; Quiles Morales, J L; Granados Principal, S; Martínez de Victoria Muñoz, E; Ortega Martos, L
Data(s)

27/11/2015

27/11/2015

2008

Resumo

The electrophoresis of cells in alkaline medium (comet assay) is a valid technique for quantifying DNA damage in patients with ataxia-telangiectasia and their relatives.

Identificador

Moreno Galarraga L, Santos Pérez JL, Ramirez-Tortosa MC, Quiles Morales JL, Granados Principal S, Martínez de Victoria Muñoz E, et al. Use of the comet test to assess DNA damage in children with ataxia-telangiectasia and their relatives. J Investig Allergol Clin Immunol . 2008; 18(2):137-8

1018-9068 (Online)

1018-9068 (Print)

http://hdl.handle.net/10668/2085

18447146

Idioma(s)

en

Publicador

ESMON Publicidad

Relação

Journal of investigational allergology & clinical immunology

http://www.jiaci.org/issues/vol18issue2/vol18issue02-12.htm

Direitos

Acceso abierto

Palavras-Chave #Ataxia-telangiectasia #DNA damage #Cancer risk #Comet tes #Daño en el ADN #Riesgo de cáncer #Prueba cometa #Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Cerebellar Diseases::Cerebellar Ataxia::Spinocerebellar Ataxias::Ataxia Telangiectasia #Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cell Cycle Proteins #Medical Subject Headings::Named Groups::Persons::Age Groups::Child #Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis::Electrophoresis, Agar Gel::Comet Assay #Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage #Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins #Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease #Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans #Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases #Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins #Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/published

Artículo