Catabolite repression control of pyocyanin biosynthesis at an intersection of primary and secondary metabolism in Pseudomonas aeruginosa.
| Data(s) |
2012
|
|---|---|
| Resumo |
In Pseudomonas aeruginosa, the catabolite repression control (Crc) protein repressed the formation of the blue pigment pyocyanin in response to a preferred carbon source (succinate) by interacting with phzM mRNA, which encodes a key enzyme in pyocyanin biosynthesis. Crc bound to an extended imperfect recognition sequence that was interrupted by the AUG translation initiation codon. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_4B52572A08E0 isbn:1098-5336 (Electronic) pmid:22562990 doi:10.1128/AEM.00026-12 isiid:000306098600031 |
| Idioma(s) |
en |
| Fonte |
Applied and Environmental Microbiology, vol. 78, no. 14, pp. 5016-5020 |
| Palavras-Chave | #Bacterial Proteins/biosynthesis; Bacterial Proteins/genetics; Catabolite Repression; Codon, Initiator; Gene Expression Regulation, Bacterial; Methyltransferases/genetics; Methyltransferases/metabolism; Pseudomonas aeruginosa/enzymology; Pseudomonas aeruginosa/genetics; Pyocyanine/biosynthesis; Pyocyanine/genetics; Repressor Proteins/genetics; Repressor Proteins/metabolism; Succinic Acid/metabolism |
| Tipo |
info:eu-repo/semantics/article article |
