Draft genome sequences of three NDM-1-producing Enterobacteriaceae species isolated from Brazil


Autoria(s): Pereira,Polyana Silva; Albano,Rodolpho Mattos; Asensi,Marise Dutra; Carvalho-Assef,Ana Paula D’Alincourt
Data(s)

01/06/2015

Resumo

The emergence of multidrug-resistant Enterobacteriaceae strains producing carbapenemases, such as NDM-1, has become a major public health issue due to a high dissemination capacity and limited treatment options. Here we describe the draft genome of three NDM-1-producing isolates: Providencia rettgeri(CCBH11880), Enterobacter hormaecheisubsp. oharae(CCBH10892) and Klebsiella pneumoniae(CCBH13327), isolated in Brazil. BesidesblaNDM-1, resistance genes to aminoglycosides [aadA1, aadA2,aac(6’)-Ib-cr] and quinolones (qnrA1,qnrB4) were observed which contributed to the multidrug resistance profile. The element ISAba125 was found associated to theblaNDM-1 gene in all strains.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000400580

Idioma(s)

en

Publicador

Instituto Oswaldo Cruz, Ministério da Saúde

Fonte

Memórias do Instituto Oswaldo Cruz v.110 n.4 2015

Palavras-Chave #NDM-1 #Brazil #Enterobacteriaceae
Tipo

journal article