Infectious diseases not immune to genome-wide association.
Data(s) |
2010
|
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Resumo |
Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations. |
Identificador |
http://serval.unil.ch/?id=serval:BIB_44F3F2C186FA isbn:1546-1718[electronic], 1061-4036[linking] pmid:20802473 doi:10.1038/ng0910-731 isiid:000281388400002 |
Idioma(s) |
en |
Fonte |
Nature Genetics, vol. 42, no. 9, pp. 731-732 |
Palavras-Chave | #Africa; Communicable Diseases/genetics; Communicable Diseases/immunology; Disease Susceptibility/immunology; Genetic Predisposition to Disease; Genetics, Population/trends; Genome-Wide Association Study/trends; Genome-Wide Association Study/utilization; Host-Pathogen Interactions/genetics; Host-Pathogen Interactions/immunology; Humans; Immunity, Innate/genetics; Infectious Disease Medicine/methods; Infectious Disease Medicine/trends |
Tipo |
info:eu-repo/semantics/article article |