Infectious diseases not immune to genome-wide association.


Autoria(s): de Bakker Paul I.; Telenti Amalio
Data(s)

2010

Resumo

Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.

Identificador

http://serval.unil.ch/?id=serval:BIB_44F3F2C186FA

isbn:1546-1718[electronic], 1061-4036[linking]

pmid:20802473

doi:10.1038/ng0910-731

isiid:000281388400002

Idioma(s)

en

Fonte

Nature Genetics, vol. 42, no. 9, pp. 731-732

Palavras-Chave #Africa; Communicable Diseases/genetics; Communicable Diseases/immunology; Disease Susceptibility/immunology; Genetic Predisposition to Disease; Genetics, Population/trends; Genome-Wide Association Study/trends; Genome-Wide Association Study/utilization; Host-Pathogen Interactions/genetics; Host-Pathogen Interactions/immunology; Humans; Immunity, Innate/genetics; Infectious Disease Medicine/methods; Infectious Disease Medicine/trends
Tipo

info:eu-repo/semantics/article

article