Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil
| Data(s) |
01/05/2013
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|---|---|
| Resumo |
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS. |
| Formato |
text/html |
| Identificador |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392 |
| Idioma(s) |
en |
| Publicador |
Instituto Oswaldo Cruz, Ministério da Saúde |
| Fonte |
Memórias do Instituto Oswaldo Cruz v.108 n.3 2013 |
| Palavras-Chave | #influenza A(H1N1)pmd09 #resistance #oseltamivir |
| Tipo |
journal article |