Of fat, β cells, and diabetes.
| Data(s) |
2011
|
|---|---|
| Resumo |
The molecular mechanisms linking diet, obesity, and type 2 diabetes are still poorly understood. In a recent paper, Ohtsubo et al. (2011) show that high lipid levels induce nuclear exclusion of Foxa2 and HNF1α in β cells, leading to impaired expression and glycosylation of proteins controlling glucose-stimulated insulin secretion. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_420709167259 isbn:1932-7420 (Electronic) pmid:21982703 doi:10.1016/j.cmet.2011.09.006 isiid:000296223600003 |
| Idioma(s) |
en |
| Fonte |
Cell Metabolism, vol. 14, no. 4, pp. 439-440 |
| Tipo |
info:eu-repo/semantics/article article |
