The L162V polymorphism of the PPARA gene is associated with stage C of heart failure.
| Data(s) |
06/06/2013
06/06/2013
2009
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| Resumo |
In human heart failure (HF) peroxisome proliferator-activated receptor alpha (PPAR alpha) is downregulated and consequently, the expression of genes involved in fatty acid oxidation repressed. The L162V (rs1800206) is a functional polymorphism of the human PPAR alpha gene (PPARA). In the present study we have investigated whether this polymorphism is associated with the development of stage C of HF. Abstract 1921. Contents: Volume 120, Issue 18 Supplement; November 3, 2009 / Abstracts From Scientific Sessions 2009 |
| Identificador |
Beaumont, Javier; Arias, Teresa; Lopez, Begona; Zalba, Guillermo; Beloqui, Oscar; Garcia-Bolao, Ignacio; et al. The L162V polymorphism of the PPARA gene is associated with stage C of heart failure. Circulation. 2009;120(18 Suppl 2):S571 0009-7322 (Print) 1524-4539 (Online) |
| Idioma(s) |
en |
| Publicador |
American Heart Association |
| Relação |
Circulation http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S571-b?sid=7b981245-4e2e-435d-a5a3-589cad6e01ac |
| Direitos |
Acceso abierto |
| Palavras-Chave | #Acil-CoA Deshidrogenasa #Cartilla de ADN #Insuficiencia Cardíaca #PPAR alfa #Humanos #Plásmidos #Polimorfismo Genético #ARN Mensajero #Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-CH Group Donors::Acyl-CoA Dehydrogenases #Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides::Polynucleotides::Oligonucleotides::Oligodeoxyribonucleotides::DNA Primers #Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Failure #Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Peroxisome Proliferator-Activated Receptors::PPAR alpha #Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans #Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Plasmids #Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic #Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger #Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/published Meeting Abstract |
