Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
| Data(s) |
2009
|
|---|---|
| Resumo |
Imipenem plasma concentrations were analyzed in 57 febrile neutropenic patients using the NONMEM program. The recommended 2-g/day regimen achieved coverage of the most common bacteria (MIC(90) = 1 mg/liter) during the whole dosing interval in only 53% of patients. This goal was achieved in 90% of patients with 3 g/day. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_3C81678B0325 isbn:1098-6596 pmid:19047655 doi:10.1128/AAC.00891-08 isiid:000262646500057 |
| Idioma(s) |
en |
| Fonte |
Antimicrobial Agents and Chemotherapy, vol. 53, no. 2, pp. 785-787 |
| Tipo |
info:eu-repo/semantics/article article |
