Contribution of clumping factor B to pathogenesis of experimental endocarditis due to Staphylococcus aureus.
| Data(s) |
2000
|
|---|---|
| Resumo |
Staphylococcus aureus Newman with an insertion mutation in clfB, the gene encoding clumping factor B, only marginally decreased infection rate (P>0.05) in rats with experimental endocarditis. In contrast, clfB complementation on a multicopy plasmid significantly increased infectivity (P<0.05) over the deleted mutants. Although clfB could affect endovascular infection, its importance in experimental endocarditis was limited. |
| Identificador |
http://serval.unil.ch/?id=serval:BIB_391AAB001D63 isbn:0019-9567 (Print) pmid:10948180 doi:10.1128/IAI.68.9.5443-5446.2000 isiid:000088870200086 |
| Idioma(s) |
en |
| Fonte |
Infection and Immunity, vol. 68, no. 9, pp. 5443-5446 |
| Palavras-Chave | #Adhesins, Bacterial/physiology; Animals; Endocarditis, Bacterial/etiology; Fibrinogen/metabolism; Rats; Staphylococcal Infections/etiology |
| Tipo |
info:eu-repo/semantics/article article |
