Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome.


Autoria(s): Martinon F.
Data(s)

2012

Resumo

Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, Shimada et al. (2012) report that oxidized DNA, released by mitochondria, directly binds and activates the NLRP3 inflammasome.

Identificador

http://serval.unil.ch/?id=serval:BIB_38FBB482D658

isbn:1097-4180 (Electronic)

pmid:22444626

doi:10.1016/j.immuni.2012.03.005

isiid:000302048400002

Idioma(s)

en

Fonte

Immunity, vol. 36, no. 3, pp. 313-315

Tipo

info:eu-repo/semantics/review

article