The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata


Autoria(s): Serrano,Deborah Regina; Zanotti-Magalhães,Eliana Maria; Magalhães,Luiz Augusto; Carvalho,José Ferreira de
Data(s)

01/09/2002

Resumo

Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024

Idioma(s)

en

Publicador

Instituto Oswaldo Cruz, Ministério da Saúde

Fonte

Memórias do Instituto Oswaldo Cruz v.97 n.6 2002

Palavras-Chave #Schistosoma mansoni #Biomphalaria glabrata #hydrocortisone #sporocyst #hemocyte reaction
Tipo

journal article